High res graphics cards handle up to 6 displays

The C420 and C680 graphics cards can run four or six monitors and feature 2 Gbytes of GDDR5 memory and secure mini DisplayPort connections. The C420 yields resolution of up to 2560 x 1600 at 60 HZ, the C680 up to 4096 x 2160 at 60 Hz. They use a PCIe 3.0 x16 bus interface.

PowerDesk desktop management software for Windows allows easily configuration and management of multi-display setups. The support OpenGL 4.4, DirectX 11.2, and OpenCL 1.2.